The NMDAR modulator NYX-2925 alleviates neuropathic pain via a Src-dependent mechanism in the mPFC

Previous studies have shown that oral administration of the NMDAR modulator NYX-2925 alleviates pain in several animal models of neuropathic pain and this appears to be through mPFC, but not spinal, mediated mechanisms. While much is known about the impact of neuropathic pain on NMDAR-mediated signa...

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Detalles Bibliográficos
Autores principales: Morrison, Gladys, Asiedu, Marina N., Priebe, Jessica M., Dunning, Jacqueline, Ghoreishi-Haack, Nayereh, Kroes, Roger A., Bowers, M. Scott, Barth, Amanda L., Cearley, Cassia N., Moskal, Joseph R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938954/
https://www.ncbi.nlm.nih.gov/pubmed/31909296
http://dx.doi.org/10.1016/j.ynpai.2019.100039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938954/
https://www.ncbi.nlm.nih.gov/pubmed/31909296
http://dx.doi.org/10.1016/j.ynpai.2019.100039

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