CFTR Therapeutics Normalize Cerebral Perfusion Deficits in Mouse Models of Heart Failure and Subarachnoid Hemorrhage

Heart failure (HF) and subarachnoid hemorrhage (SAH) chronically reduce cerebral perfusion, which negatively affects clinical outcome. This work demonstrates a strong relationship between cerebral artery cystic fibrosis transmembrane conductance regulator (CFTR) expression and altered cerebrovascula...

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Detalles Bibliográficos
Autores principales: Lidington, Darcy, Fares, Jessica C., Uhl, Franziska E., Dinh, Danny D., Kroetsch, Jeffrey T., Sauvé, Meghan, Malik, Firhan A., Matthes, Frank, Vanherle, Lotte, Adel, Arman, Momen, Abdul, Zhang, Hangjun, Aschar-Sobbi, Roozbeh, Foltz, Warren D., Wan, Hoyee, Sumiyoshi, Manabu, Macdonald, R. Loch, Husain, Mansoor, Backx, Peter H., Heximer, Scott P., Meissner, Anja, Bolz, Steffen-Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Editorial Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939007/
https://www.ncbi.nlm.nih.gov/pubmed/31909302
http://dx.doi.org/10.1016/j.jacbts.2019.07.004

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