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Inhibition of miR-155-5p Exerts Anti-Fibrotic Effects in Silicotic Mice by Regulating Meprin α

Silicosis is a fatal profession-related disease linked to long-term inhalation of silica. The present study aimed to determine whether meprin α, a master regulator of anti-fibrotic peptide N-acetyl-seryl-aspartyl-lysyl-proline (Ac-SDKP), is diminished by miR-155-5p in silicotic and control lung macr...

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Detalles Bibliográficos
Autores principales: Chen, Yingying, Xu, Dingjie, Yao, Jingxin, Wei, Zhongqiu, Li, Shifeng, Gao, Xuemin, Cai, Wenchen, Mao, Na, Jin, Fuyu, Li, Yaqian, Zhu, Ying, Li, Shumin, Liu, Heliang, Yang, Fang, Xu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939030/
https://www.ncbi.nlm.nih.gov/pubmed/31877411
http://dx.doi.org/10.1016/j.omtn.2019.11.018