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Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report

INTRODUCTION: Comorbid Alzheimer disease pathologies are frequently found in people with Down syndrome (DS). We report a deep phenotyping study undertaken over 7 years in a participant with DS who was nondemented at baseline but developed dementia after 5 years. METHODS: Throughout the course of the...

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Detalles Bibliográficos
Autores principales: Mak, Elijah, Bickerton, Anastasia, Padilla, Concepcion, Walpert, Madeleine J., Annus, Tiina, Wilson, Liam R., Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Menon, David K., Nestor, Peter J., Zaman, Shahid H., Holland, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939035/
https://www.ncbi.nlm.nih.gov/pubmed/31909173
http://dx.doi.org/10.1016/j.dadm.2019.04.006

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