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Longitudinal trajectories of amyloid deposition, cortical thickness, and tau in Down syndrome: A deep-phenotyping case report
INTRODUCTION: Comorbid Alzheimer disease pathologies are frequently found in people with Down syndrome (DS). We report a deep phenotyping study undertaken over 7 years in a participant with DS who was nondemented at baseline but developed dementia after 5 years. METHODS: Throughout the course of the...
Autores principales: | Mak, Elijah, Bickerton, Anastasia, Padilla, Concepcion, Walpert, Madeleine J., Annus, Tiina, Wilson, Liam R., Hong, Young T., Fryer, Tim D., Coles, Jonathan P., Aigbirhio, Franklin I., Christian, Bradley T., Handen, Benjamin L., Klunk, William E., Menon, David K., Nestor, Peter J., Zaman, Shahid H., Holland, Anthony J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939035/ https://www.ncbi.nlm.nih.gov/pubmed/31909173 http://dx.doi.org/10.1016/j.dadm.2019.04.006 |
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