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The Translation of Non-Canonical Open Reading Frames Controls Mucosal Immunity

The annotation of the mammalian protein coding genome is incomplete. Arbitrary open reading frame (ORF) size restriction and the absolute requirement for a methionine codon as the sole initiator of translation, have constrained identification of potentially important transcripts with non-canonical p...

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Detalles Bibliográficos
Autores principales: Jackson, Ruaidhrí, Kroehling, Lina, Khitun, Alexandra, Bailis, Will, Jarret, Abigail, York, Autumn G., Khan, Omair M., Brewer, J. Richard, Skadow, Mathias H., Duizer, Coco, Harman, Christian C. D., Chang, Lelina, Bielecki, Piotr, Solis, Angel G., Steach, Holly R., Slavoff, Sarah, Flavell, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939389/
https://www.ncbi.nlm.nih.gov/pubmed/30542152
http://dx.doi.org/10.1038/s41586-018-0794-7