Cargando…

Tumor and nodal staging of colon cancer: accuracy of preoperative computed tomography at a Swedish high-volume center

BACKGROUND: When deciding treatment options for patients with colon cancer, accurate staging is required. In Sweden, the main preoperative evaluation modality to determine tumor and nodal stage is computed tomography (CT). PURPOSE: The aim of this study was to investigate how well the preoperative (...

Descripción completa

Detalles Bibliográficos
Autores principales: Korsbakke, Kevin, Dahlbäck, Cecilia, Karlsson, Niklas, Zackrisson, Sophia, Buchwald, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939391/
https://www.ncbi.nlm.nih.gov/pubmed/31921464
http://dx.doi.org/10.1177/2058460119888713
_version_ 1783484201916432384
author Korsbakke, Kevin
Dahlbäck, Cecilia
Karlsson, Niklas
Zackrisson, Sophia
Buchwald, Pamela
author_facet Korsbakke, Kevin
Dahlbäck, Cecilia
Karlsson, Niklas
Zackrisson, Sophia
Buchwald, Pamela
author_sort Korsbakke, Kevin
collection PubMed
description BACKGROUND: When deciding treatment options for patients with colon cancer, accurate staging is required. In Sweden, the main preoperative evaluation modality to determine tumor and nodal stage is computed tomography (CT). PURPOSE: The aim of this study was to investigate how well the preoperative (CT-determined) clinical tumor and nodal stage (cTN) correlated with the postoperative histopathological stage (pTN). Another aim was to validate the tumor and nodal stage data in the Swedish Colorectal Cancer Registry (SCRCR). MATERIAL AND METHODS: The SCRCR was used to identify patients with colon cancer, treated at a Swedish high-volume center during 2013–2016 (n = 974). Data were gathered from medical records regarding cTN and pTN stage, and predefined patient and tumor variables. The agreement between cTN and pTN was analyzed using kappa statistics. RESULTS: After excluding patients with either pre- or postoperative TN stage missing, 383 patients remained for further analyses. The analyses showed an agreement between cT and pT of κ: 0.27 and between cN and pN of κ: 0.21 (fair agreement). When comparing tumors with low (T1–3; N0) versus high risk (T4; N1–2), the kappa value was 0.19 (slight agreement). When comparing the SCRCR to medical records, 78% of completely staged tumors had been correctly reported. CONCLUSION: The agreement between cTN and pTN was low in this study population, indicating a need for enhanced precision of the preoperative staging process. A high frequency of erroneous preoperative staging data in the SCRCR shows the need for further efforts of ensuring correct data transfers into the registry.
format Online
Article
Text
id pubmed-6939391
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher SAGE Publications
record_format MEDLINE/PubMed
spelling pubmed-69393912020-01-09 Tumor and nodal staging of colon cancer: accuracy of preoperative computed tomography at a Swedish high-volume center Korsbakke, Kevin Dahlbäck, Cecilia Karlsson, Niklas Zackrisson, Sophia Buchwald, Pamela Acta Radiol Open Original Article BACKGROUND: When deciding treatment options for patients with colon cancer, accurate staging is required. In Sweden, the main preoperative evaluation modality to determine tumor and nodal stage is computed tomography (CT). PURPOSE: The aim of this study was to investigate how well the preoperative (CT-determined) clinical tumor and nodal stage (cTN) correlated with the postoperative histopathological stage (pTN). Another aim was to validate the tumor and nodal stage data in the Swedish Colorectal Cancer Registry (SCRCR). MATERIAL AND METHODS: The SCRCR was used to identify patients with colon cancer, treated at a Swedish high-volume center during 2013–2016 (n = 974). Data were gathered from medical records regarding cTN and pTN stage, and predefined patient and tumor variables. The agreement between cTN and pTN was analyzed using kappa statistics. RESULTS: After excluding patients with either pre- or postoperative TN stage missing, 383 patients remained for further analyses. The analyses showed an agreement between cT and pT of κ: 0.27 and between cN and pN of κ: 0.21 (fair agreement). When comparing tumors with low (T1–3; N0) versus high risk (T4; N1–2), the kappa value was 0.19 (slight agreement). When comparing the SCRCR to medical records, 78% of completely staged tumors had been correctly reported. CONCLUSION: The agreement between cTN and pTN was low in this study population, indicating a need for enhanced precision of the preoperative staging process. A high frequency of erroneous preoperative staging data in the SCRCR shows the need for further efforts of ensuring correct data transfers into the registry. SAGE Publications 2019-12-30 /pmc/articles/PMC6939391/ /pubmed/31921464 http://dx.doi.org/10.1177/2058460119888713 Text en © The Foundation Acta Radiologica 2019 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Original Article
Korsbakke, Kevin
Dahlbäck, Cecilia
Karlsson, Niklas
Zackrisson, Sophia
Buchwald, Pamela
Tumor and nodal staging of colon cancer: accuracy of preoperative computed tomography at a Swedish high-volume center
title Tumor and nodal staging of colon cancer: accuracy of preoperative computed tomography at a Swedish high-volume center
title_full Tumor and nodal staging of colon cancer: accuracy of preoperative computed tomography at a Swedish high-volume center
title_fullStr Tumor and nodal staging of colon cancer: accuracy of preoperative computed tomography at a Swedish high-volume center
title_full_unstemmed Tumor and nodal staging of colon cancer: accuracy of preoperative computed tomography at a Swedish high-volume center
title_short Tumor and nodal staging of colon cancer: accuracy of preoperative computed tomography at a Swedish high-volume center
title_sort tumor and nodal staging of colon cancer: accuracy of preoperative computed tomography at a swedish high-volume center
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939391/
https://www.ncbi.nlm.nih.gov/pubmed/31921464
http://dx.doi.org/10.1177/2058460119888713
work_keys_str_mv AT korsbakkekevin tumorandnodalstagingofcoloncanceraccuracyofpreoperativecomputedtomographyataswedishhighvolumecenter
AT dahlbackcecilia tumorandnodalstagingofcoloncanceraccuracyofpreoperativecomputedtomographyataswedishhighvolumecenter
AT karlssonniklas tumorandnodalstagingofcoloncanceraccuracyofpreoperativecomputedtomographyataswedishhighvolumecenter
AT zackrissonsophia tumorandnodalstagingofcoloncanceraccuracyofpreoperativecomputedtomographyataswedishhighvolumecenter
AT buchwaldpamela tumorandnodalstagingofcoloncanceraccuracyofpreoperativecomputedtomographyataswedishhighvolumecenter