IRF1 Negatively Regulates Oncogenic KPNA2 Expression Under Growth Stimulation and Hypoxia in Lung Cancer Cells

PURPOSE: Karyopherin alpha 2 (KPNA2) has been reported as an oncogenic protein in numerous human cancers and is currently considered a potential therapeutic target. However, the transcriptional regulation and physiological conditions underlying KPNA2 expression remain unclear. The aim of the present...

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Detalles Bibliográficos
Autores principales: Huang, Jie-Xin, Wu, Yi-Cheng, Cheng, Ya-Yun, Wang, Chih-Liang, Yu, Chia-Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939401/
https://www.ncbi.nlm.nih.gov/pubmed/31920336
http://dx.doi.org/10.2147/OTT.S221832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939401/
https://www.ncbi.nlm.nih.gov/pubmed/31920336
http://dx.doi.org/10.2147/OTT.S221832

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