The Oncogenic Kaposi’s Sarcoma-Associated Herpesvirus Encodes a Mimic of the Tumor-Suppressive miR-15/16 miRNA Family

Many tumor viruses encode oncogenes of cellular origin. Here, we report an oncoviral mimic of a cellular tumor suppressor. The Kaposi’s sarcoma-associated herpesvirus (KSHV) microRNA (miRNA) miR-K6-5p shares sequence similarity to the tumor-suppressive cellular miR-15/16 miRNA family. We show that m...

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Detalles Bibliográficos
Autores principales: Morrison, Kylee, Manzano, Mark, Chung, Kevin, Schipma, Matthew J., Bartom, Elizabeth T., Gottwein, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939447/
https://www.ncbi.nlm.nih.gov/pubmed/31801064
http://dx.doi.org/10.1016/j.celrep.2019.11.005

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