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Cell-Based IL-15:IL-15Rα Secreting Vaccine as an Effective Therapy for CT26 Colon Cancer in Mice

Interleukin (IL)-15 is an essential immune-modulator with high potential for use in cancer treatment. Natural IL-15 has a low biological potency because of its short half-life and difficulties in mass-production. IL-15Rα, a member of the IL-15 receptor complex, is famous for its high affinity to IL-...

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Detalles Bibliográficos
Autores principales: Thi, Van Anh Do, Jeon, Hyung Min, Park, Sang Min, Lee, Hayyoung, Kim, Young Sang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939657/
https://www.ncbi.nlm.nih.gov/pubmed/31760731
http://dx.doi.org/10.14348/molcells.2019.0188