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Modulation of Immunosuppression by Oligonucleotide-Based Molecules and Small Molecules Targeting Myeloid-Derived Suppressor Cells

Myeloid-derived suppressor cells (MDSCs) are immature myeloid cells that exert suppressive function on the immune response. MDSCs expand in tumor-bearing hosts or in the tumor microenvironment and suppress T cell responses via various mechanisms, whereas a reduction in their activities has been obse...

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Detalles Bibliográficos
Autores principales: Lim, Jihyun, Lee, Aram, Lee, Hee Gu, Lim, Jong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939693/
https://www.ncbi.nlm.nih.gov/pubmed/31431006
http://dx.doi.org/10.4062/biomolther.2019.069