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Behavioral and Subjective Effects of Reducing Nicotine in Cigarettes: A Cessation Commentary

This commentary addresses critical questions regarding the impact of the reduction of nicotine on changes in smoking behavior. There appears to be moderate evidence that use of reduced nicotine cigarettes (RNC) increases the likelihood of making a quit attempt among smokers unmotivated to quit and a...

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Autores principales: Piper, Megan E, Drobes, David J, Walker, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939774/
https://www.ncbi.nlm.nih.gov/pubmed/31867644
http://dx.doi.org/10.1093/ntr/ntz100
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author Piper, Megan E
Drobes, David J
Walker, Natalie
author_facet Piper, Megan E
Drobes, David J
Walker, Natalie
author_sort Piper, Megan E
collection PubMed
description This commentary addresses critical questions regarding the impact of the reduction of nicotine on changes in smoking behavior. There appears to be moderate evidence that use of reduced nicotine cigarettes (RNC) increases the likelihood of making a quit attempt among smokers unmotivated to quit and among smokers motivated to quit who also used nicotine replacement therapy (NRT). There was limited evidence that RNC combined with NRT increased smoking abstinence, regardless of motivation to quit. Several plausible mechanisms via which RNC may influence smoking behavior, including reducing dependence, are reviewed. The moderate evidence that abrupt reduction in nicotine reduces self-reported dependence as well as smoking behavior and likelihood of relapse is also reviewed. The data reviewed here suggest that abrupt switching to, and extended use of, RNC can reduce cigarette dependence and several related constructs, including the ability to quit smoking. The data reviewed in this commentary suggest that abrupt reduction in the level of nicotine in combustible cigarettes could reduce smoking behavior, nicotine dependence, and other related constructs and increase quit attempts and eventual smoking cessation.
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spelling pubmed-69397742020-01-07 Behavioral and Subjective Effects of Reducing Nicotine in Cigarettes: A Cessation Commentary Piper, Megan E Drobes, David J Walker, Natalie Nicotine Tob Res Maximum Level of Nicotine and Other Constituents: Effects on Behavior This commentary addresses critical questions regarding the impact of the reduction of nicotine on changes in smoking behavior. There appears to be moderate evidence that use of reduced nicotine cigarettes (RNC) increases the likelihood of making a quit attempt among smokers unmotivated to quit and among smokers motivated to quit who also used nicotine replacement therapy (NRT). There was limited evidence that RNC combined with NRT increased smoking abstinence, regardless of motivation to quit. Several plausible mechanisms via which RNC may influence smoking behavior, including reducing dependence, are reviewed. The moderate evidence that abrupt reduction in nicotine reduces self-reported dependence as well as smoking behavior and likelihood of relapse is also reviewed. The data reviewed here suggest that abrupt switching to, and extended use of, RNC can reduce cigarette dependence and several related constructs, including the ability to quit smoking. The data reviewed in this commentary suggest that abrupt reduction in the level of nicotine in combustible cigarettes could reduce smoking behavior, nicotine dependence, and other related constructs and increase quit attempts and eventual smoking cessation. Oxford University Press 2019-12 2019-12-23 /pmc/articles/PMC6939774/ /pubmed/31867644 http://dx.doi.org/10.1093/ntr/ntz100 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of the Society for Research on Nicotine and Tobacco. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Maximum Level of Nicotine and Other Constituents: Effects on Behavior
Piper, Megan E
Drobes, David J
Walker, Natalie
Behavioral and Subjective Effects of Reducing Nicotine in Cigarettes: A Cessation Commentary
title Behavioral and Subjective Effects of Reducing Nicotine in Cigarettes: A Cessation Commentary
title_full Behavioral and Subjective Effects of Reducing Nicotine in Cigarettes: A Cessation Commentary
title_fullStr Behavioral and Subjective Effects of Reducing Nicotine in Cigarettes: A Cessation Commentary
title_full_unstemmed Behavioral and Subjective Effects of Reducing Nicotine in Cigarettes: A Cessation Commentary
title_short Behavioral and Subjective Effects of Reducing Nicotine in Cigarettes: A Cessation Commentary
title_sort behavioral and subjective effects of reducing nicotine in cigarettes: a cessation commentary
topic Maximum Level of Nicotine and Other Constituents: Effects on Behavior
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939774/
https://www.ncbi.nlm.nih.gov/pubmed/31867644
http://dx.doi.org/10.1093/ntr/ntz100
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