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Genetic predisposition to celiac disease in Kazakhstan: Potential impact on the clinical practice in Central Asia

BACKGROUND: Celiac disease (CD) is a systemic immune-mediated disorder developing in HLA genetically predisposed individuals carrying HLA-DQ2 and/or HLA-DQ8 molecules. Recent evidences supported a predominant importance of HLA-DQB1 locus and, in particular, HLA-DQB1*02 alleles. This diagnosis is poo...

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Detalles Bibliográficos
Autores principales:	Poddighe, Dimitri, Turganbekova, Aida, Baymukasheva, Dana, Saduakas, Zhazira, Zhanzakova, Zhuldyz, Abdrakhmanova, Saniya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939901/ https://www.ncbi.nlm.nih.gov/pubmed/31895924 http://dx.doi.org/10.1371/journal.pone.0226546

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