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Generation and application of patient-derived xenograft models in pancreatic cancer research

OBJECTIVE: Pancreatic ductal adenocarcinoma cancer (PDAC) is one of the leading causes of cancer-related death worldwide. Hence, the development of effective anti-PDAC therapies is urgently required. Patient-derived xenograft (PDX) models are useful models for developing anti-cancer therapies and sc...

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Detalles Bibliográficos
Autores principales: Wang, Cheng-Fang, Shi, Xian-Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940092/
https://www.ncbi.nlm.nih.gov/pubmed/31725451
http://dx.doi.org/10.1097/CM9.0000000000000524