FGF2 engineered SPIONs attenuate tumor stroma and potentiate the effect of chemotherapy in 3D heterospheroidal model of pancreatic tumor

Pancreatic ductal adenocarcinoma (PDAC), characterized with abundant tumor stroma, is a highly malignant tumor with poor prognosis. The tumor stroma largely consists of cancer-associated fibroblasts (CAFs) and extracellular matrix (ECM), and is known to promote tumor growth and progression as well a...

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Detalles Bibliográficos
Autores principales: Mardhian, Deby Fajar, Vrynas, Aggelos, Storm, Gert, Bansal, Ruchi, Prakash, Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940204/
https://www.ncbi.nlm.nih.gov/pubmed/31911892
http://dx.doi.org/10.7150/ntno.38092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940204/
https://www.ncbi.nlm.nih.gov/pubmed/31911892
http://dx.doi.org/10.7150/ntno.38092

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