Association between fatigue and motor progression in Parkinson’s disease in southern Chinese

STUDY OBJECTIVES: The aim was to investigate whether fatigue could predict the development of motor symptoms of Parkinson’s disease (PD) in a southern Chinese population. METHODS: In total, 246 PD patients were recruited. All patients were evaluated by Fatigue Severity Scale (FSS), Hamilton Anxiety...

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Detalles Bibliográficos
Autores principales: Yu, Hong-Xiang, Guo, Meng-Ruo, Li, Gang, Zhang, Bei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940320/
https://www.ncbi.nlm.nih.gov/pubmed/31485861
http://dx.doi.org/10.1007/s10072-019-04059-z
Descripción
Sumario:STUDY OBJECTIVES: The aim was to investigate whether fatigue could predict the development of motor symptoms of Parkinson’s disease (PD) in a southern Chinese population. METHODS: In total, 246 PD patients were recruited. All patients were evaluated by Fatigue Severity Scale (FSS), Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, and Unified PD Rating Scale provided by Movement Disorders Society (MDS-UPDRS). MDS-UPDRS was re-evaluated after 2 years. RESULTS: FSS scores were associated with total score and subparts of MDS-UPDRS (total: p 0.039, p 0.030, adjusted; part III: p 0.022, p 0.016, adjusted). CONCLUSIONS: The symptom of subjective fatigue could predict the progression of PD.

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