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Enhanced Anticancer Effect of Adding Magnesium to Vitamin C Therapy: Inhibition of Hormetic Response by SVCT-2 Activation
l-Ascorbic acid (vitamin C, AA) is known as an antioxidant, but at high concentrations, AA can kill cancer cells through a prooxidant property. Sodium-dependent vitamin C transporter family-2 (SVCT-2) determines the cellular uptake of AA, and the activity of SVCT-2 is directly related to the antican...
Autores principales: | Cho, Sungrae, Chae, Jin Sung, Shin, Hocheol, Shin, Yujeong, Kim, Youngwook, Kil, Eui-Joon, Byun, Hee-Seong, Cho, Sang-Ho, Park, Seyeon, Lee, Sukchan, Yeom, Chang-Hwan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940627/ https://www.ncbi.nlm.nih.gov/pubmed/31901552 http://dx.doi.org/10.1016/j.tranon.2019.10.017 |
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