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In Vitro and MD Simulation Study to Explore Physicochemical Parameters for Antibacterial Peptide to Become Potent Anticancer Peptide

Although the physicochemical properties of antimicrobial peptides (AMPs) and anticancer peptides (ACPs) are very similar, it remains unclear which specific parameter(s) of ACPs confer the major anticancer activity. By answering how to construct a short AMP/ACP that could easily be synthesized in the...

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Detalles Bibliográficos
Autores principales: Ma, Rui, Wong, Sin Wa, Ge, Lilin, Shaw, Chris, Siu, Shirley W.I., Kwok, Hang Fai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940675/
https://www.ncbi.nlm.nih.gov/pubmed/31909181
http://dx.doi.org/10.1016/j.omto.2019.12.001