Altered DNA methylation of TRIM13 in diabetic nephropathy suppresses mesangial collagen synthesis by promoting ubiquitination of CHOP

BACKGROUND: Mesangial collagen synthesis in renal glomeruli contributes to the pathogenesis of diabetic nephropathy (DN) which is one of the most serious complications of diabetes mellitus. However, the underlying mechanism of mesangial collagen synthesis is largely unknown. METHODS: The differentia...

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Detalles Bibliográficos
Autores principales: Li, Yebei, Ren, Daijin, Shen, Yunfeng, Zheng, Xiaoxu, Xu, Gaosi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940716/
https://www.ncbi.nlm.nih.gov/pubmed/31901873
http://dx.doi.org/10.1016/j.ebiom.2019.11.043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940716/
https://www.ncbi.nlm.nih.gov/pubmed/31901873
http://dx.doi.org/10.1016/j.ebiom.2019.11.043

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