Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vi...

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Detalles Bibliográficos
Autores principales: Espanhol, Clarissa Mitri, Recuero, Júlia Kanaan, Pagani, Danielle Machado, Ribeiro, Amanda Carvalho, Vettorato, Gerson, Duquia, Rodrigo Pereira, Luzzatto, Laura, Scroferneker, Maria Lúcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940718/
https://www.ncbi.nlm.nih.gov/pubmed/31908912
http://dx.doi.org/10.1016/j.mmcr.2019.12.003
Descripción
Sumario:We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vitro revealed terbinafine as the best antifungal. For treatment, it was chosen surgical excision of the entire lesion and used systemic itraconazole. Phaeohyphomycosis caused by Exophiala xenobiotica is extremely rare and is closely related to transplant patients.

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