Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report

We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vi...

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Autores principales: Espanhol, Clarissa Mitri, Recuero, Júlia Kanaan, Pagani, Danielle Machado, Ribeiro, Amanda Carvalho, Vettorato, Gerson, Duquia, Rodrigo Pereira, Luzzatto, Laura, Scroferneker, Maria Lúcia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940718/
https://www.ncbi.nlm.nih.gov/pubmed/31908912
http://dx.doi.org/10.1016/j.mmcr.2019.12.003
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author Espanhol, Clarissa Mitri
Recuero, Júlia Kanaan
Pagani, Danielle Machado
Ribeiro, Amanda Carvalho
Vettorato, Gerson
Duquia, Rodrigo Pereira
Luzzatto, Laura
Scroferneker, Maria Lúcia
author_facet Espanhol, Clarissa Mitri
Recuero, Júlia Kanaan
Pagani, Danielle Machado
Ribeiro, Amanda Carvalho
Vettorato, Gerson
Duquia, Rodrigo Pereira
Luzzatto, Laura
Scroferneker, Maria Lúcia
author_sort Espanhol, Clarissa Mitri
collection PubMed
description We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vitro revealed terbinafine as the best antifungal. For treatment, it was chosen surgical excision of the entire lesion and used systemic itraconazole. Phaeohyphomycosis caused by Exophiala xenobiotica is extremely rare and is closely related to transplant patients.
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spelling pubmed-69407182020-01-06 Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report Espanhol, Clarissa Mitri Recuero, Júlia Kanaan Pagani, Danielle Machado Ribeiro, Amanda Carvalho Vettorato, Gerson Duquia, Rodrigo Pereira Luzzatto, Laura Scroferneker, Maria Lúcia Med Mycol Case Rep Case Report We report a case of phaeohyphomycosis that affected the leg of a 45-year-old Brazilian man, car mechanic and renal transplanted. The direct mycological examination evidenced dematiaceous septated hyphae. The pathogenic fungal species was identified as Exophiala xenobiotica. Antifungal activity in vitro revealed terbinafine as the best antifungal. For treatment, it was chosen surgical excision of the entire lesion and used systemic itraconazole. Phaeohyphomycosis caused by Exophiala xenobiotica is extremely rare and is closely related to transplant patients. Elsevier 2019-12-26 /pmc/articles/PMC6940718/ /pubmed/31908912 http://dx.doi.org/10.1016/j.mmcr.2019.12.003 Text en © 2019 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Espanhol, Clarissa Mitri
Recuero, Júlia Kanaan
Pagani, Danielle Machado
Ribeiro, Amanda Carvalho
Vettorato, Gerson
Duquia, Rodrigo Pereira
Luzzatto, Laura
Scroferneker, Maria Lúcia
Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report
title Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report
title_full Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report
title_fullStr Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report
title_full_unstemmed Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report
title_short Cutaneous phaeohyphomycosis caused by Exophiala xenobiotica: A case report
title_sort cutaneous phaeohyphomycosis caused by exophiala xenobiotica: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940718/
https://www.ncbi.nlm.nih.gov/pubmed/31908912
http://dx.doi.org/10.1016/j.mmcr.2019.12.003
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