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A Novel, Tumor-Induced Osteoclastogenesis Pathway Insensitive to Denosumab but Interfered by Cannabidiol
Bone metabolism is strictly regulated, and impaired regulation caused by hormonal imbalances induces systemic bone loss. Local bone loss caused by tumor invasion into bone is suggested to be induced by the generation of cytokines, which affect bone metabolism, by tumor cells. The major cause of syst...
Autores principales: | Tsuchiya, Maiko, Kayamori, Kou, Wada, Akane, Komaki, Motohiro, Ohata, Yae, Hamagaki, Miwako, Sakamoto, Kei, Ikeda, Tohru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940789/ https://www.ncbi.nlm.nih.gov/pubmed/31835378 http://dx.doi.org/10.3390/ijms20246211 |
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