The Challenge of Bringing iPSCs to the Patient

The implementation of induced pluripotent stem cells (iPSCs) in biomedical research more than a decade ago, resulted in a huge leap forward in the highly promising area of personalized medicine. Nowadays, we are even closer to the patient than ever. To date, there are multiple examples of iPSCs appl...

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Detalles Bibliográficos
Autores principales: Ortuño-Costela, María del Carmen, Cerrada, Victoria, García-López, Marta, Gallardo, M. Esther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940848/
https://www.ncbi.nlm.nih.gov/pubmed/31847153
http://dx.doi.org/10.3390/ijms20246305
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author Ortuño-Costela, María del Carmen
Cerrada, Victoria
García-López, Marta
Gallardo, M. Esther
author_facet Ortuño-Costela, María del Carmen
Cerrada, Victoria
García-López, Marta
Gallardo, M. Esther
author_sort Ortuño-Costela, María del Carmen
collection PubMed
description The implementation of induced pluripotent stem cells (iPSCs) in biomedical research more than a decade ago, resulted in a huge leap forward in the highly promising area of personalized medicine. Nowadays, we are even closer to the patient than ever. To date, there are multiple examples of iPSCs applications in clinical trials and drug screening. However, there are still many obstacles to overcome. In this review, we will focus our attention on the advantages of implementing induced pluripotent stem cells technology into the clinics but also commenting on all the current drawbacks that could hinder this promising path towards the patient.
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spelling pubmed-69408482020-01-09 The Challenge of Bringing iPSCs to the Patient Ortuño-Costela, María del Carmen Cerrada, Victoria García-López, Marta Gallardo, M. Esther Int J Mol Sci Review The implementation of induced pluripotent stem cells (iPSCs) in biomedical research more than a decade ago, resulted in a huge leap forward in the highly promising area of personalized medicine. Nowadays, we are even closer to the patient than ever. To date, there are multiple examples of iPSCs applications in clinical trials and drug screening. However, there are still many obstacles to overcome. In this review, we will focus our attention on the advantages of implementing induced pluripotent stem cells technology into the clinics but also commenting on all the current drawbacks that could hinder this promising path towards the patient. MDPI 2019-12-13 /pmc/articles/PMC6940848/ /pubmed/31847153 http://dx.doi.org/10.3390/ijms20246305 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ortuño-Costela, María del Carmen
Cerrada, Victoria
García-López, Marta
Gallardo, M. Esther
The Challenge of Bringing iPSCs to the Patient
title The Challenge of Bringing iPSCs to the Patient
title_full The Challenge of Bringing iPSCs to the Patient
title_fullStr The Challenge of Bringing iPSCs to the Patient
title_full_unstemmed The Challenge of Bringing iPSCs to the Patient
title_short The Challenge of Bringing iPSCs to the Patient
title_sort challenge of bringing ipscs to the patient
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940848/
https://www.ncbi.nlm.nih.gov/pubmed/31847153
http://dx.doi.org/10.3390/ijms20246305
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