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Circulating Extracellular Vesicles Containing Xenobiotic Metabolizing CYP Enzymes and Their Potential Roles in Extrahepatic Cells Via Cell–Cell Interactions

The cytochrome P450 (CYP) family of enzymes is known to metabolize the majority of xenobiotics. Hepatocytes, powerhouses of CYP enzymes, are where most drugs are metabolized into non-toxic metabolites. Additional tissues/cells such as gut, kidneys, lungs, blood, and brain cells express selective CYP...

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Detalles Bibliográficos
Autores principales:	Gerth, Kelli, Kodidela, Sunitha, Mahon, Madeline, Haque, Sanjana, Verma, Neha, Kumar, Santosh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940889/ https://www.ncbi.nlm.nih.gov/pubmed/31817878 http://dx.doi.org/10.3390/ijms20246178

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