Cargando…

Windup of Nociceptive Flexion Reflex Depends on Synaptic and Intrinsic Properties of Dorsal Horn Neurons in Adult Rats

Windup, a progressive increase in spinal response to repetitive stimulations of nociceptive peripheral fibers, is a useful model to study central sensitization to pain. Windup is expressed by neurons in both the dorsal and ventral horn of the spinal cord. In juvenile rats, it has been demonstrated b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aby, Franck, Bouali-Benazzouz, Rabia, Landry, Marc, Fossat, Pascal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940907/ https://www.ncbi.nlm.nih.gov/pubmed/31817540 http://dx.doi.org/10.3390/ijms20246146

Ejemplares similares

Group I metabotropic glutamate receptor plasticity after peripheral inflammation alters nociceptive transmission in the dorsal horn of the spinal cord in adult rats
por: Radwani, Houda, et al.
Publicado: (2017)

Inflammatory-induced spinal dorsal horn neurons hyperexcitability is mediated by P2X4 receptors
por: Aby, Franck, et al.
Publicado: (2018)

Turtle Flexion Reflex Motor Patterns Show Windup, Mediated Partly by L-type Calcium Channels
por: Johnson, Keith P., et al.
Publicado: (2017)

Pain hypersensitivity in a pharmacological mouse model of attention-deficit/hyperactivity disorder
por: Bouchatta, Otmane, et al.
Publicado: (2022)

Effects of measurement posture and stimulation intensity on the nociceptive flexion reflex (RIII reflex)
por: Lee, Jeong-Woo, et al.
Publicado: (2017)

Is blood glucose associated with descending modulation of spinal nociception as measured by the nociceptive flexion reflex?
por: Terry, Ellen L, et al.
Publicado: (2016)

Serotonergic Modulation of Nociceptive Circuits in Spinal Cord Dorsal Horn
por: Bardoni, Rita
Publicado: (2019)

Chemokine CCL2 prevents opioid-induced inhibition of nociceptive synaptic transmission in spinal cord dorsal horn
por: Heles, Mario, et al.
Publicado: (2021)

The Path to Discovery of Windup and Central Sensitization
por: Mendell, Lorne M.
Publicado: (2022)

Neonatal 6-OHDA lesion model in mouse induces Attention-Deficit/ Hyperactivity Disorder (ADHD)-like behaviour
por: Bouchatta, Otmane, et al.
Publicado: (2018)

Synchronous firing of dorsal horn neurons at the origin of dorsal root reflexes in naïve and paw-inflamed mice
por: Lucas-Romero, Javier, et al.
Publicado: (2022)

Central expression of synaptophysin and synaptoporin in nociceptive afferent subtypes in the dorsal horn
por: Chung, Jumi, et al.
Publicado: (2019)

The Cellular and Synaptic Architecture of the Mechanosensory Dorsal Horn
por: Abraira, Victoria E., et al.
Publicado: (2017)

Postnatal Temporal, Spatial and Modality Tuning of Nociceptive Cutaneous Flexion Reflexes in Human Infants
por: Cornelissen, Laura, et al.
Publicado: (2013)

Phorbol Ester Modulation of Ca(2+) Channels Mediates Nociceptive Transmission in Dorsal Horn Neurones
por: Yang, Li, et al.
Publicado: (2013)

Somatotopy in the Medullary Dorsal Horn As a Basis for Orofacial Reflex Behavior
por: Panneton, W. Michael, et al.
Publicado: (2017)

Slack K(Na) channels influence dorsal horn synapses and nociceptive behavior
por: Evely, Katherine M, et al.
Publicado: (2017)

Contrasting alterations to synaptic and intrinsic properties in upper-cervical superficial dorsal horn neurons following acute neck muscle inflammation
por: Harris, Belinda M, et al.
Publicado: (2014)

Periaqueductal grey cyclooxygenase-dependent facilitation of C-nociceptive drive and encoding in dorsal horn neurons in the rat
por: Leith, J Lianne, et al.
Publicado: (2014)

Pain-related synaptic plasticity in spinal dorsal horn neurons: role of CGRP
por: Bird, Gary C, et al.
Publicado: (2006)

Morphological, biophysical and synaptic properties of glutamatergic neurons of the mouse spinal dorsal horn
por: Punnakkal, Pradeep, et al.
Publicado: (2014)

Synaptic Targets of Glycinergic Neurons in Laminae I–III of the Spinal Dorsal Horn
por: Miranda, Camila Oliveira, et al.
Publicado: (2023)

Measurement of the nociceptive flexion reflex threshold in critically ill patients – a randomized observational pilot study
por: Schick, Benedikt, et al.
Publicado: (2021)

Switch of serotonergic descending inhibition into facilitation by a spinal chloride imbalance in neuropathic pain
por: Aby, Franck, et al.
Publicado: (2022)

Discovery of Prostamide F(2α) and Its Role in Inflammatory Pain and Dorsal Horn Nociceptive Neuron Hyperexcitability
por: Gatta, Luisa, et al.
Publicado: (2012)

Inhibition of electroacupuncture on nociceptive responses of dorsal horn neurons evoked by noxious colorectal distention in an intensity-dependent manner
por: Yu, Lingling, et al.
Publicado: (2019)

Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture
por: Hendrich, Janek, et al.
Publicado: (2012)

Impact of Propofol Bolus Administration on the Nociceptive Flexion Reflex Threshold and Bispectral Index in Children—A Case Series
por: Mauritz, Maximilian David, et al.
Publicado: (2021)

Altered Intrinsic Properties and Inhibitory Connectivity in Aged Parvalbumin-Expressing Dorsal Horn Neurons
por: Gradwell, Mark A., et al.
Publicado: (2022)

Analysis of the mechanisms underlying windup using a detailed biophysical model of WDR neurons
por: Aguiar, Paulo, et al.
Publicado: (2010)

Synaptically evoked glutamate transporter currents in Spinal Dorsal Horn Astrocytes
por: Zhang, Haijun, et al.
Publicado: (2009)

Regulation of Nociceptive Plasticity Threshold and DARPP-32 Phosphorylation in Spinal Dorsal Horn Neurons by Convergent Dopamine and Glutamate Inputs
por: Buesa, Itsaso, et al.
Publicado: (2016)

Synaptic Connections of the Neurokinin 1 Receptor-Like Immunoreactive Neurons in the Rat Medullary Dorsal Horn
por: Qi, Jian, et al.
Publicado: (2011)

Mitochondrial superoxide increases excitatory synaptic strength in spinal dorsal horn neurons of neuropathic mice
por: Bae, Chilman, et al.
Publicado: (2018)

Neuronal intrinsic properties shape naturally evoked sensory inputs in the dorsal horn of the spinal cord
por: Reali, Cecilia, et al.
Publicado: (2013)

Strong Manual Acupuncture Manipulation Could Better Inhibit Spike Frequency of the Dorsal Horn Neurons in Rats with Acute Visceral Nociception
por: Hong, Shouhai, et al.
Publicado: (2015)

Modulation of GABAergic Synaptic Transmission by NMDA Receptors in the Dorsal Horn of the Spinal Cord
por: Leonardon, Benjamin, et al.
Publicado: (2022)

Fibromyalgia and Nociceptive Flexion Reflex (NFR) Threshold: A Systematic Review, Meta-Analysis, and Identification of a Possible Source of Heterogeneity
por: Amiri, Mohammadreza, et al.
Publicado: (2021)

Robust MFC anti-windup scheme for LTI systems with norm-bounded uncertainty
por: Mo, Xiao-Qin, et al.
Publicado: (2021)

Reduction in inhibitory control is sufficient to generate hyperalgesia in a spiking model of nociceptive integration in the superficial dorsal horn
por: Sousa, Mafalda, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_idsvpgavmlg3o9vsfjvo4h06j8