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Genetic Programs Driving Oncogenic Transformation: Lessons from In Vitro Models

Cancer complexity relies on the intracellular pleiotropy of oncogenes/tumor suppressors and in the strong interplay between tumors and micro- and macro-environments. Here we followed a reductionist approach, by analyzing the transcriptional adaptations induced by three oncogenes (RAS, MYC, and HDAC4...

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Detalles Bibliográficos
Autores principales: Di Giorgio, Eros, Paluvai, Harikrishnareddy, Picco, Raffaella, Brancolini, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940909/
https://www.ncbi.nlm.nih.gov/pubmed/31842516
http://dx.doi.org/10.3390/ijms20246283