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Natural Flavonol, Myricetin, Enhances the Function and Survival of Cryopreserved Hepatocytes In Vitro and In Vivo

To improve the therapeutic potential of hepatocyte transplantation, the effects of the mitogen-activated protein kinase kinase 4 (MKK4) inhibitor, myricetin (3,3′,4′,5,5′,7-hexahydroxylflavone) were examined using porcine and human hepatocytes in vitro and in vivo. Hepatocytes were cultured, showing...

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Detalles Bibliográficos
Autores principales: Cui, Changhao, Enosawa, Shin, Matsunari, Hitomi, Nagashima, Hiroshi, Umezawa, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6940939/
https://www.ncbi.nlm.nih.gov/pubmed/31817281
http://dx.doi.org/10.3390/ijms20246123