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Cancer Cell-Derived Granulocyte-Macrophage Colony-Stimulating Factor Is Dispensable for the Progression of 4T1 Murine Breast Cancer

We previously reported that 4T1 murine breast cancer cells produce GM-CSF that up-regulates macrophage expression of several cancer promoting genes, including Mcp-1/Ccl2, Ccl17 and Rankl, suggesting a critical role of cancer cell-derived GM-CSF in cancer progression. Here, we attempted to define whe...

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Detalles Bibliográficos
Autores principales: Yoshimura, Teizo, Nakamura, Kaoru, Li, Chunning, Fujisawa, Masayoshi, Shiina, Tsuyoshi, Imamura, Mayu, Li, Tiantian, Mukaida, Naofumi, Matsukawa, Akihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941073/
https://www.ncbi.nlm.nih.gov/pubmed/31888216
http://dx.doi.org/10.3390/ijms20246342