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Glucose Tolerance-Improving Activity of Helichrysoside in Mice and Its Structural Requirements for Promoting Glucose and Lipid Metabolism

An acylated flavonol glycoside, helichrysoside, at a dose of 10 mg/kg/day per os for 14 days, improved the glucose tolerance in mice without affecting the food intake, visceral fat weight, liver weight, and other plasma parameters. In this study, using hepatoblastoma-derived HepG2 cells, helichrysos...

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Detalles Bibliográficos
Autores principales: Morikawa, Toshio, Nagatomo, Akifumi, Oka, Takahiro, Miki, Yoshinobu, Taira, Norihisa, Shibano-Kitahara, Megumi, Hori, Yuichiro, Muraoka, Osamu, Ninomiya, Kiyofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941121/
https://www.ncbi.nlm.nih.gov/pubmed/31847420
http://dx.doi.org/10.3390/ijms20246322