Protein Abundance Biases the Amino Acid Composition of Disordered Regions to Minimize Non-functional Interactions

In eukaryotes, disordered regions cover up to 50% of proteomes and mediate fundamental cellular processes. In contrast to globular domains, where about half of the amino acids are buried in the protein interior, disordered regions show higher solvent accessibility, which makes them prone to engage i...

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Detalles Bibliográficos
Autores principales: Dubreuil, Benjamin, Matalon, Or, Levy, Emmanuel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941228/
https://www.ncbi.nlm.nih.gov/pubmed/31442477
http://dx.doi.org/10.1016/j.jmb.2019.08.008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941228/
https://www.ncbi.nlm.nih.gov/pubmed/31442477
http://dx.doi.org/10.1016/j.jmb.2019.08.008

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