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Protein Abundance Biases the Amino Acid Composition of Disordered Regions to Minimize Non-functional Interactions
In eukaryotes, disordered regions cover up to 50% of proteomes and mediate fundamental cellular processes. In contrast to globular domains, where about half of the amino acids are buried in the protein interior, disordered regions show higher solvent accessibility, which makes them prone to engage i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941228/ https://www.ncbi.nlm.nih.gov/pubmed/31442477 http://dx.doi.org/10.1016/j.jmb.2019.08.008 |