Patient-derived xenografts of different grade gliomas retain the heterogeneous histological and genetic features of human gliomas

BACKGROUND: Gliomas account for the major part of primary brain tumors. Based on their histology and molecular alternations, adult gliomas have been classified into four grades, each with distinct biology and outcome. Previous studies have focused on cell-line-based models and patient-derived xenogr...

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Detalles Bibliográficos
Autores principales: Zeng, Wenxin, Tang, Zhaohua, Li, Yongguo, Yin, Guangnian, Liu, Zili, Gao, Jie, Chen, Yan, Chen, Feilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941273/
https://www.ncbi.nlm.nih.gov/pubmed/31908598
http://dx.doi.org/10.1186/s12935-019-1086-5

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