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Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer’s disease

BACKGROUND: Plasma and cerebrospinal fluid levels of neurofilament light (NfL), a marker of axonal degeneration, have previously been reported to be raised in patients with clinically diagnosed Alzheimer’s disease (AD). Activated microglia, an intrinsic inflammatory response to brain lesions, are al...

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Detalles Bibliográficos
Autores principales:	Parbo, Peter, Madsen, Lasse Stensvig, Ismail, Rola, Zetterberg, Henrik, Blennow, Kaj, Eskildsen, Simon F., Vorup-Jensen, Thomas, Brooks, David J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941285/ https://www.ncbi.nlm.nih.gov/pubmed/31898549 http://dx.doi.org/10.1186/s13195-019-0574-0

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