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Flow cytometry and targeted immune transcriptomics identify distinct profiles in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors with or without interferon-α

BACKGROUND: Tumor cells have evolved complex strategies to escape immune surveillance, a process which involves NK cells and T lymphocytes, and various immunological factors. Indeed, tumor cells recruit immunosuppressive cells [including regulatory T-cells (Treg), myeloid-derived suppressor cells (M...

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Detalles Bibliográficos
Autores principales: Alves, Raquel, McArdle, Stephanie E. B., Vadakekolathu, Jayakumar, Gonçalves, Ana Cristina, Freitas-Tavares, Paulo, Pereira, Amélia, Almeida, Antonio M., Sarmento-Ribeiro, Ana Bela, Rutella, Sergio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941328/
https://www.ncbi.nlm.nih.gov/pubmed/31900171
http://dx.doi.org/10.1186/s12967-019-02194-x

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