Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A

The construction of the biologically interesting chromone skeleton was realized by PhIO-mediated dehydrogenation of chromanones under mild conditions. Interestingly, this method also found application in the synthesis of the naturally occurring frutinone A.

Detalles Bibliográficos
Autores principales: Li, Qiao, Zhuang, Chen, Wang, Donghua, Zhang, Wei, Jia, Rongxuan, Sun, Fengxia, Zhang, Yilin, Du, Yunfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941426/
https://www.ncbi.nlm.nih.gov/pubmed/31921367
http://dx.doi.org/10.3762/bjoc.15.291
_version_ 1783484551588216832
author Li, Qiao
Zhuang, Chen
Wang, Donghua
Zhang, Wei
Jia, Rongxuan
Sun, Fengxia
Zhang, Yilin
Du, Yunfei
author_facet Li, Qiao
Zhuang, Chen
Wang, Donghua
Zhang, Wei
Jia, Rongxuan
Sun, Fengxia
Zhang, Yilin
Du, Yunfei
author_sort Li, Qiao
collection PubMed
description The construction of the biologically interesting chromone skeleton was realized by PhIO-mediated dehydrogenation of chromanones under mild conditions. Interestingly, this method also found application in the synthesis of the naturally occurring frutinone A.
format Online
Article
Text
id pubmed-6941426
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher Beilstein-Institut
record_format MEDLINE/PubMed
spelling pubmed-69414262020-01-09 Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A Li, Qiao Zhuang, Chen Wang, Donghua Zhang, Wei Jia, Rongxuan Sun, Fengxia Zhang, Yilin Du, Yunfei Beilstein J Org Chem Letter The construction of the biologically interesting chromone skeleton was realized by PhIO-mediated dehydrogenation of chromanones under mild conditions. Interestingly, this method also found application in the synthesis of the naturally occurring frutinone A. Beilstein-Institut 2019-12-12 /pmc/articles/PMC6941426/ /pubmed/31921367 http://dx.doi.org/10.3762/bjoc.15.291 Text en Copyright © 2019, Li et al. https://creativecommons.org/licenses/by/4.0https://www.beilstein-journals.org/bjoc/termsThis is an Open Access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0). Please note that the reuse, redistribution and reproduction in particular requires that the authors and source are credited. The license is subject to the Beilstein Journal of Organic Chemistry terms and conditions: (https://www.beilstein-journals.org/bjoc/terms)
spellingShingle Letter
Li, Qiao
Zhuang, Chen
Wang, Donghua
Zhang, Wei
Jia, Rongxuan
Sun, Fengxia
Zhang, Yilin
Du, Yunfei
Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A
title Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A
title_full Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A
title_fullStr Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A
title_full_unstemmed Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A
title_short Construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via PhIO-mediated dehydrogenation and its application to the synthesis of frutinone A
title_sort construction of trisubstituted chromone skeletons carrying electron-withdrawing groups via phio-mediated dehydrogenation and its application to the synthesis of frutinone a
topic Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941426/
https://www.ncbi.nlm.nih.gov/pubmed/31921367
http://dx.doi.org/10.3762/bjoc.15.291
work_keys_str_mv AT liqiao constructionoftrisubstitutedchromoneskeletonscarryingelectronwithdrawinggroupsviaphiomediateddehydrogenationanditsapplicationtothesynthesisoffrutinonea
AT zhuangchen constructionoftrisubstitutedchromoneskeletonscarryingelectronwithdrawinggroupsviaphiomediateddehydrogenationanditsapplicationtothesynthesisoffrutinonea
AT wangdonghua constructionoftrisubstitutedchromoneskeletonscarryingelectronwithdrawinggroupsviaphiomediateddehydrogenationanditsapplicationtothesynthesisoffrutinonea
AT zhangwei constructionoftrisubstitutedchromoneskeletonscarryingelectronwithdrawinggroupsviaphiomediateddehydrogenationanditsapplicationtothesynthesisoffrutinonea
AT jiarongxuan constructionoftrisubstitutedchromoneskeletonscarryingelectronwithdrawinggroupsviaphiomediateddehydrogenationanditsapplicationtothesynthesisoffrutinonea
AT sunfengxia constructionoftrisubstitutedchromoneskeletonscarryingelectronwithdrawinggroupsviaphiomediateddehydrogenationanditsapplicationtothesynthesisoffrutinonea
AT zhangyilin constructionoftrisubstitutedchromoneskeletonscarryingelectronwithdrawinggroupsviaphiomediateddehydrogenationanditsapplicationtothesynthesisoffrutinonea
AT duyunfei constructionoftrisubstitutedchromoneskeletonscarryingelectronwithdrawinggroupsviaphiomediateddehydrogenationanditsapplicationtothesynthesisoffrutinonea

Ejemplares similares