Cargando…

Metallochaperones Are Needed for Mycobacterium tuberculosis and Escherichia coli Nicotinamidase-Pyrazinamidase Activity

Mycobacterium tuberculosis nicotinamidase-pyrazinamidase (PZAse) is a metalloenzyme that catalyzes conversion of nicotinamide-pyrazinamide to nicotinic acid-pyrazinoic acid. This study investigated whether a metallochaperone is required for optimal PZAse activity. M. tuberculosis and Escherichia col...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sheen, Patricia, Monsalve, Anuntxi, Campos, Jhanina, Huerta, Rodolfo, Antiparra, Ricardo, Arteaga, Héctor, Duran, Patricia, Bueno, Carlos, Kirwan, Daniela E., Gilman, Robert H., Zimic, Mirko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941528/ https://www.ncbi.nlm.nih.gov/pubmed/31636108 http://dx.doi.org/10.1128/JB.00331-19

Ejemplares similares

Structure-Activity relationship in mutated pyrazinamidases from Mycobacterium tuberculosis
por: Quiliano, Miguel, et al.
Publicado: (2011)

Prediction of Mycobacterium tuberculosis pyrazinamidase function based on structural stability, physicochemical and geometrical descriptors
por: Supo-Escalante, Rydberg Roman, et al.
Publicado: (2020)

Molecular Dynamics Simulations Suggest Ligand’s Binding to Nicotinamidase/Pyrazinamidase
por: Zhang, Ji-Long, et al.
Publicado: (2012)

MODS-Wayne, a Colorimetric Adaptation of the Microscopic-Observation Drug Susceptibility (MODS) Assay for Detection of Mycobacterium tuberculosis Pyrazinamide Resistance from Sputum Samples
por: Alcántara, Roberto, et al.
Publicado: (2019)

Combined Whole-Cell High-Throughput Functional Screening for Identification of New Nicotinamidases/Pyrazinamidases in Metagenomic/Polygenomic Libraries
por: Zapata-Pérez, Rubén, et al.
Publicado: (2016)

Detecting Mutations in the Mycobacterium tuberculosis Pyrazinamidase Gene pncA to Improve Infection Control and Decrease Drug Resistance Rates in Human Immunodeficiency Virus Coinfection
por: Dudley, Matthew Z., et al.
Publicado: (2016)

Immunological detection of pyrazine-2-carboxylic acid for the detection of pyrazinamide resistance in Mycobacterium tuberculosis
por: Florentini, Edgar A., et al.
Publicado: (2020)

Metal-Ion Effects on the Polarization of Metal-Bound Water and Infrared Vibrational Modes of the Coordinated Metal Center of Mycobacterium tuberculosis Pyrazinamidase via Quantum Mechanical Calculations
por: Salazar-Salinas, Karim, et al.
Publicado: (2014)

Correction: Immunological detection of pyrazine-2-carboxylic acid for the detection of pyrazinamide resistance in Mycobacterium tuberculosis
por: Florentini, Edgar A., et al.
Publicado: (2021)

Quantitative (1)H Nuclear Magnetic Resonance Assay for the Rapid Detection of Pyrazinamide Resistance in Mycobacterium tuberculosis from Sputum Samples
por: Lopez, Juan M., et al.
Publicado: (2023)

Mycobacterium tuberculosis ribosomal protein S1 (RpsA) and variants with truncated C-terminal end show absence of interaction with pyrazinoic acid
por: Vallejos-Sánchez, Katherine, et al.
Publicado: (2020)

Determination of Potentially Novel Compensatory Mutations in rpoC Associated with Rifampin Resistance and rpoB Mutations in Mycobacterium tuberculosis Clinical Isolates from Peru
por: Vargas, Ana Paula, et al.
Publicado: (2020)

Direct Determination of Pyrazinamide (PZA) Susceptibility by Sputum Microscopic Observation Drug Susceptibility (MODS) Culture at Neutral pH: the MODS-PZA Assay
por: Alcántara, Roberto, et al.
Publicado: (2020)

A multiple genome analysis of Mycobacterium tuberculosis reveals specific novel genes and mutations associated with pyrazinamide resistance
por: Sheen, Patricia, et al.
Publicado: (2017)

Crystal Structure of the Pyrazinamidase of Mycobacterium tuberculosis: Insights into Natural and Acquired Resistance to Pyrazinamide
por: Petrella, Stéphanie, et al.
Publicado: (2011)

Converting the E. coli Isochorismatase Nicotinamidase into γ-Lactamase
por: Guo, Xiaoyan, et al.
Publicado: (2022)

Plasmodium falciparum Nicotinamidase as A Novel Antimalarial Target
por: Donu, Dickson, et al.
Publicado: (2022)

Development of Low-Cost Inverted Microscope to Detect Early Growth of Mycobacterium tuberculosis in MODS Culture
por: Zimic, Mirko, et al.
Publicado: (2010)

Genetic Diversity of Mycobacterium tuberculosis in Peru and Exploration of Phylogenetic Associations with Drug Resistance
por: Sheen, Patricia, et al.
Publicado: (2013)

An electrochemical biosensor for the detection of Mycobacterium tuberculosis DNA from sputum and urine samples
por: Ramos-Sono, Daniel, et al.
Publicado: (2020)

Insights into Pyrazinamidase and DNA Gyrase Protein Structures in Resistant and Susceptible Clinical Isolates of Mycobacterium tuberculosis
por: Ahmadi, Azam, et al.
Publicado: (2016)

Metallochaperones Regulate Intracellular Copper Levels
por: Pang, W. Lee, et al.
Publicado: (2013)

Mechanistic analysis elucidating the relationship between Lys96 mutation in Mycobacterium tuberculosis pyrazinamidase enzyme and pyrazinamide susceptibility
por: Vats, Chakshu, et al.
Publicado: (2015)

Determining the unbinding events and conserved motions associated with the pyrazinamide release due to resistance mutations of Mycobacterium tuberculosis pyrazinamidase
por: Sheik Amamuddy, Olivier, et al.
Publicado: (2020)

Mathematical algorithm for the automatic recognition of intestinal parasites
por: Alva, Alicia, et al.
Publicado: (2017)

Automatic diagnostics of tuberculosis using convolutional neural networks analysis of MODS digital images
por: Lopez-Garnier, Santiago, et al.
Publicado: (2019)

Morphological Characterization of Mycobacterium tuberculosis in a MODS Culture for an Automatic Diagnostics through Pattern Recognition
por: Alva, Alicia, et al.
Publicado: (2013)

The role of nucleoside triphosphate hydrolase metallochaperones in making metalloenzymes
por: Vaccaro, Francesca A, et al.
Publicado: (2022)

Biochemical and Mutational Analysis of a Novel Nicotinamidase from Oceanobacillus iheyensis HTE831
por: Sánchez-Carrón, Guiomar, et al.
Publicado: (2013)

A Multi-Scale Computational Study on the Mechanism of Streptococcus pneumoniae Nicotinamidase (SpNic)
por: Ion, Bogdan F., et al.
Publicado: (2014)

FOXO1 regulates pentose phosphate pathway-mediated induction of developmental erythropoiesis
por: Monsalve, Anuntxi, et al.
Publicado: (2022)

Immunoinformatics prediction of linear epitopes from Taenia solium TSOL18
por: Zimic, Mirko, et al.
Publicado: (2011)

Environment and coordination of FeMo–co in the nitrogenase metallochaperone NafY
por: Phillips, Aaron H., et al.
Publicado: (2021)

A novel mode of control of nickel uptake by a multifunctional metallochaperone
por: Denic, Milica, et al.
Publicado: (2021)

The Association between Mycobacterium Tuberculosis Genotype and Drug Resistance in Peru
por: Grandjean, Louis, et al.
Publicado: (2015)

The relative fitness of drug-resistant Mycobacterium tuberculosis: a modelling study of household transmission in Peru
por: Knight, Gwenan M., et al.
Publicado: (2018)

Assembly and phylogeographical analysis of novel Taenia solium mitochondrial genomes suggest stratification within the African-American genotype
por: Jiménez-Avalos, Gabriel, et al.
Publicado: (2023)

The SlyD metallochaperone targets iron-sulfur biogenesis pathways and the TCA cycle
por: Denic, Milica, et al.
Publicado: (2023)

Zinc Metallochaperones as Mutant p53 Reactivators: A New Paradigm in Cancer Therapeutics
por: Kogan, Samuel, et al.
Publicado: (2018)

Structural basis and mechanism for metallochaperone-assisted assembly of the Cu(A) center in cytochrome oxidase
por: Canonica, Fabia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_33ia9f3ebvqvi19jisorpaqvdm