Unfolded Protein Response and Cancer

Physiological stresses, such as hypoxia and oxidative stress, induce protein misfolding in the endoplasmic reticulum (ER). If proteasome degradation fails to remove the misfolded proteins, these proteins accumulate in the ER, triggering the unfolded protein response (UPR). UPR involves a series of r...

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Detalles Bibliográficos
Autores principales: Wu, Lihua, Chou, Mary, Zhu, Shudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Applied Systems srl 2014
Materias:
Focused Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941583/
https://www.ncbi.nlm.nih.gov/pubmed/32309542
http://dx.doi.org/10.15190/d.2014.2

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