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A genome alignment of 120 mammals highlights ultraconserved element variability and placenta-associated enhancers

BACKGROUND: Multiple alignments of mammalian genomes have been the basis of many comparative genomic studies aiming at annotating genes, detecting regions under evolutionary constraint, and studying genome evolution. A key factor that affects the power of comparative analyses is the number of specie...

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Detalles Bibliográficos
Autores principales: Hecker, Nikolai, Hiller, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941714/
https://www.ncbi.nlm.nih.gov/pubmed/31899510
http://dx.doi.org/10.1093/gigascience/giz159