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The Yin and Yang of RNA surveillance in B lymphocytes and antibody-secreting plasma cells
The random V(D)J recombination process ensures the diversity of the primary immunoglobulin (Ig) repertoire. In two thirds of cases, imprecise recombination between variable (V), diversity (D), and joining (J) segments induces a frameshift in the open reading frame that leads to the appearance of pre...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Korean Society for Biochemistry and Molecular Biology
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941761/ https://www.ncbi.nlm.nih.gov/pubmed/31619318 http://dx.doi.org/10.5483/BMBRep.2019.52.12.232 |