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Genome-wide DNA methylomic differences between dorsolateral prefrontal and temporal pole cortices of bipolar disorder

Dorsolateral prefrontal cortex (DLPFC) and temporal pole (TP) are brain regions that display abnormalities in bipolar disorder (BD) patients. DNA methylation — an epigenetic mechanism both heritable and sensitive to the environment — may be involved in the pathophysiology of BD. To study BD-associat...

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Detalles Bibliográficos
Autores principales: Ho, Ada M.-C., Winham, Stacey J., Armasu, Sebastian M., Blacker, Caren J., Millischer, Vincent, Lavebratt, Catharina, Overholser, James C., Jurjus, George J., Dieter, Lesa, Mahajan, Gouri, Rajkowska, Grazyna, Vallender, Eric J., Stockmeier, Craig A., Robertson, Keith D., Frye, Mark A., Choi, Doo-Sup, Veldic, Marin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941851/
https://www.ncbi.nlm.nih.gov/pubmed/31279243
http://dx.doi.org/10.1016/j.jpsychires.2019.05.030