PRMT5 Cooperates with pICln to Function as a Master Epigenetic Activator of DNA Double-Strand Break Repair Genes

DNA double-strand break (DSB) repair is critical for cell survival and genome integrity. Upon recognition of DSBs, repair proteins are transiently upregulated to facilitate repair through homologous recombination (HR) or non-homologous end joining (NHEJ). We present evidence that PRMT5 cooperates wi...

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Detalles Bibliográficos
Autores principales: Owens, Jake L., Beketova, Elena, Liu, Sheng, Tinsley, Samantha L., Asberry, Andrew M., Deng, Xuehong, Huang, Jiaoti, Li, Chenglong, Wan, Jun, Hu, Chang-Deng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6941881/
https://www.ncbi.nlm.nih.gov/pubmed/31884170
http://dx.doi.org/10.1016/j.isci.2019.100750

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