Cell-type-specific dysregulation of RNA alternative splicing in short tandem repeat mouse knockin models of myotonic dystrophy

Short tandem repeats (STRs) are prone to expansion mutations that cause multiple hereditary neurological and neuromuscular diseases. To study pathomechanisms using mouse models that recapitulate the tissue specificity and developmental timing of an STR expansion gene, we used rolling circle amplific...

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Detalles Bibliográficos
Autores principales: Nutter, Curtis A., Bubenik, Jodi L., Oliveira, Ruan, Ivankovic, Franjo, Sznajder, Łukasz J., Kidd, Benjamin M., Pinto, Belinda S., Otero, Brittney A., Carter, Helmut A., Vitriol, Eric A., Wang, Eric T., Swanson, Maurice S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942047/
https://www.ncbi.nlm.nih.gov/pubmed/31624084
http://dx.doi.org/10.1101/gad.328963.119

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