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Dual functions of angiopoietin-like protein 2 signaling in tumor progression and anti-tumor immunity

Angiopoietin-like protein 2 (ANGPTL2) is a secreted glycoprotein homologous to angiopoietins. Previous studies suggest that tumor cell-derived ANGPTL2 has tumor-promoting function. Here, we conducted mechanistic analysis comparing ANGPTL2 function in cancer progression in a murine syngeneic model of...

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Detalles Bibliográficos
Autores principales: Horiguchi, Haruki, Kadomatsu, Tsuyoshi, Kurahashi, Ryoma, Hara, Chiaki, Miyata, Keishi, Baba, Masaya, Osumi, Hironobu, Terada, Kazutoyo, Araki, Kimi, Takai, Toshiyuki, Kamba, Tomomi, Linehan, W. Marston, Moroishi, Toshiro, Oike, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942048/
https://www.ncbi.nlm.nih.gov/pubmed/31727773
http://dx.doi.org/10.1101/gad.329417.119