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Paralytic, the Drosophila voltage-gated sodium channel, regulates proliferation of neural progenitors

Proliferating cells, typically considered “nonexcitable,” nevertheless, exhibit regulation by bioelectric signals. Notably, voltage-gated sodium channels (VGSC) that are crucial for neuronal excitability are also found in progenitors and up-regulated in cancer. Here, we identify a role for VGSC in p...

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Detalles Bibliográficos
Autores principales: Piggott, Beverly J., Peters, Christian J., He, Ye, Huang, Xi, Younger, Susan, Jan, Lily Yeh, Jan, Yuh Nung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942049/
https://www.ncbi.nlm.nih.gov/pubmed/31753914
http://dx.doi.org/10.1101/gad.330597.119