Cargando…

Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results

Abdominal recurrences of renal cell carcinoma (RCC) after surgery might represent a challenge for treatment, often requiring difficult surgeries or anticipated systemic therapy. Our aim is to illustrate a novel application of laser ablation for the treatment of abdominal recurrences of RCC. Patients...

Descripción completa

Detalles Bibliográficos
Autores principales: Ferrari, Federica, Mauri, Giovanni, Nicosia, Luca, Varano, Gianluca Maria, Bonomo, Guido, Orsi, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942064/
https://www.ncbi.nlm.nih.gov/pubmed/31900683
http://dx.doi.org/10.1186/s41747-019-0127-0
_version_ 1783484646975078400
author Ferrari, Federica
Mauri, Giovanni
Nicosia, Luca
Varano, Gianluca Maria
Bonomo, Guido
Orsi, Franco
author_facet Ferrari, Federica
Mauri, Giovanni
Nicosia, Luca
Varano, Gianluca Maria
Bonomo, Guido
Orsi, Franco
author_sort Ferrari, Federica
collection PubMed
description Abdominal recurrences of renal cell carcinoma (RCC) after surgery might represent a challenge for treatment, often requiring difficult surgeries or anticipated systemic therapy. Our aim is to illustrate a novel application of laser ablation for the treatment of abdominal recurrences of RCC. Patients with abdominal recurrences of renal cancer were treated under ultrasound/computed tomography guidance with a diode laser inserted into the lesion through a thin 21-G needle. A fixed 3-W power protocol was used, changing the illumination time according to lesion dimension and shape. Also, technical success, technical efficacy, local tumour progression, and major and minor complications were retrospectively analysed. Three patients were treated with image-guided laser ablation for abdominal recurrences of RCC. In all cases, it was possible to perform ablation as preoperatively planned and all three nodules (size of 6, 8, and 12 mm) were completely ablated with no evidence of residual enhancement after 6 weeks at contrast-enhanced CT. No minor or major complications were observed. No local tumour progression was reported up to 12 months from ablation. Image-guided laser ablation holds the potential to offer a minimally invasive treatment to patients with abdominal recurrence of RCC. Further studies are needed to evaluate the clinical role of this technique.
format Online
Article
Text
id pubmed-6942064
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Springer International Publishing
record_format MEDLINE/PubMed
spelling pubmed-69420642020-01-16 Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results Ferrari, Federica Mauri, Giovanni Nicosia, Luca Varano, Gianluca Maria Bonomo, Guido Orsi, Franco Eur Radiol Exp Technical Note Abdominal recurrences of renal cell carcinoma (RCC) after surgery might represent a challenge for treatment, often requiring difficult surgeries or anticipated systemic therapy. Our aim is to illustrate a novel application of laser ablation for the treatment of abdominal recurrences of RCC. Patients with abdominal recurrences of renal cancer were treated under ultrasound/computed tomography guidance with a diode laser inserted into the lesion through a thin 21-G needle. A fixed 3-W power protocol was used, changing the illumination time according to lesion dimension and shape. Also, technical success, technical efficacy, local tumour progression, and major and minor complications were retrospectively analysed. Three patients were treated with image-guided laser ablation for abdominal recurrences of RCC. In all cases, it was possible to perform ablation as preoperatively planned and all three nodules (size of 6, 8, and 12 mm) were completely ablated with no evidence of residual enhancement after 6 weeks at contrast-enhanced CT. No minor or major complications were observed. No local tumour progression was reported up to 12 months from ablation. Image-guided laser ablation holds the potential to offer a minimally invasive treatment to patients with abdominal recurrence of RCC. Further studies are needed to evaluate the clinical role of this technique. Springer International Publishing 2020-01-03 /pmc/articles/PMC6942064/ /pubmed/31900683 http://dx.doi.org/10.1186/s41747-019-0127-0 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Technical Note
Ferrari, Federica
Mauri, Giovanni
Nicosia, Luca
Varano, Gianluca Maria
Bonomo, Guido
Orsi, Franco
Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results
title Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results
title_full Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results
title_fullStr Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results
title_full_unstemmed Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results
title_short Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results
title_sort image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results
topic Technical Note
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942064/
https://www.ncbi.nlm.nih.gov/pubmed/31900683
http://dx.doi.org/10.1186/s41747-019-0127-0
work_keys_str_mv AT ferrarifederica imageguidedlaserablationinthetreatmentofrecurrenceofrenaltumourstechniqueandpreliminaryresults
AT maurigiovanni imageguidedlaserablationinthetreatmentofrecurrenceofrenaltumourstechniqueandpreliminaryresults
AT nicosialuca imageguidedlaserablationinthetreatmentofrecurrenceofrenaltumourstechniqueandpreliminaryresults
AT varanogianlucamaria imageguidedlaserablationinthetreatmentofrecurrenceofrenaltumourstechniqueandpreliminaryresults
AT bonomoguido imageguidedlaserablationinthetreatmentofrecurrenceofrenaltumourstechniqueandpreliminaryresults
AT orsifranco imageguidedlaserablationinthetreatmentofrecurrenceofrenaltumourstechniqueandpreliminaryresults