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Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results
Abdominal recurrences of renal cell carcinoma (RCC) after surgery might represent a challenge for treatment, often requiring difficult surgeries or anticipated systemic therapy. Our aim is to illustrate a novel application of laser ablation for the treatment of abdominal recurrences of RCC. Patients...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942064/ https://www.ncbi.nlm.nih.gov/pubmed/31900683 http://dx.doi.org/10.1186/s41747-019-0127-0 |
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author | Ferrari, Federica Mauri, Giovanni Nicosia, Luca Varano, Gianluca Maria Bonomo, Guido Orsi, Franco |
author_facet | Ferrari, Federica Mauri, Giovanni Nicosia, Luca Varano, Gianluca Maria Bonomo, Guido Orsi, Franco |
author_sort | Ferrari, Federica |
collection | PubMed |
description | Abdominal recurrences of renal cell carcinoma (RCC) after surgery might represent a challenge for treatment, often requiring difficult surgeries or anticipated systemic therapy. Our aim is to illustrate a novel application of laser ablation for the treatment of abdominal recurrences of RCC. Patients with abdominal recurrences of renal cancer were treated under ultrasound/computed tomography guidance with a diode laser inserted into the lesion through a thin 21-G needle. A fixed 3-W power protocol was used, changing the illumination time according to lesion dimension and shape. Also, technical success, technical efficacy, local tumour progression, and major and minor complications were retrospectively analysed. Three patients were treated with image-guided laser ablation for abdominal recurrences of RCC. In all cases, it was possible to perform ablation as preoperatively planned and all three nodules (size of 6, 8, and 12 mm) were completely ablated with no evidence of residual enhancement after 6 weeks at contrast-enhanced CT. No minor or major complications were observed. No local tumour progression was reported up to 12 months from ablation. Image-guided laser ablation holds the potential to offer a minimally invasive treatment to patients with abdominal recurrence of RCC. Further studies are needed to evaluate the clinical role of this technique. |
format | Online Article Text |
id | pubmed-6942064 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-69420642020-01-16 Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results Ferrari, Federica Mauri, Giovanni Nicosia, Luca Varano, Gianluca Maria Bonomo, Guido Orsi, Franco Eur Radiol Exp Technical Note Abdominal recurrences of renal cell carcinoma (RCC) after surgery might represent a challenge for treatment, often requiring difficult surgeries or anticipated systemic therapy. Our aim is to illustrate a novel application of laser ablation for the treatment of abdominal recurrences of RCC. Patients with abdominal recurrences of renal cancer were treated under ultrasound/computed tomography guidance with a diode laser inserted into the lesion through a thin 21-G needle. A fixed 3-W power protocol was used, changing the illumination time according to lesion dimension and shape. Also, technical success, technical efficacy, local tumour progression, and major and minor complications were retrospectively analysed. Three patients were treated with image-guided laser ablation for abdominal recurrences of RCC. In all cases, it was possible to perform ablation as preoperatively planned and all three nodules (size of 6, 8, and 12 mm) were completely ablated with no evidence of residual enhancement after 6 weeks at contrast-enhanced CT. No minor or major complications were observed. No local tumour progression was reported up to 12 months from ablation. Image-guided laser ablation holds the potential to offer a minimally invasive treatment to patients with abdominal recurrence of RCC. Further studies are needed to evaluate the clinical role of this technique. Springer International Publishing 2020-01-03 /pmc/articles/PMC6942064/ /pubmed/31900683 http://dx.doi.org/10.1186/s41747-019-0127-0 Text en © The Author(s) 2019 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. |
spellingShingle | Technical Note Ferrari, Federica Mauri, Giovanni Nicosia, Luca Varano, Gianluca Maria Bonomo, Guido Orsi, Franco Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results |
title | Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results |
title_full | Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results |
title_fullStr | Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results |
title_full_unstemmed | Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results |
title_short | Image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results |
title_sort | image-guided laser ablation in the treatment of recurrence of renal tumours: technique and preliminary results |
topic | Technical Note |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942064/ https://www.ncbi.nlm.nih.gov/pubmed/31900683 http://dx.doi.org/10.1186/s41747-019-0127-0 |
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