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Map2k7 Haploinsufficiency Induces Brain Imaging Endophenotypes and Behavioral Phenotypes Relevant to Schizophrenia

c-Jun N-terminal kinase (JNK) signaling contributes to functional plasticity in the brain and cognition. Accumulating evidence implicates a role for MAP kinase kinase 7 (MAP2K7), a JNK activator encoded by the Map2k7 gene, and other JNK pathway components in schizophrenia (ScZ). Mice haploinsufficie...

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Detalles Bibliográficos
Autores principales:	Openshaw, Rebecca L, Thomson, David M, Thompson, Rhiannon, Penninger, Josef M, Pratt, Judith A, Morris, Brian J, Dawson, Neil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Regular Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942167/ https://www.ncbi.nlm.nih.gov/pubmed/31219577 http://dx.doi.org/10.1093/schbul/sbz044

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