Elevated HDAC activity and altered histone phospho-acetylation confer acquired radio-resistant phenotype to breast cancer cells

BACKGROUND: Poor-responsiveness of tumors to radiotherapy is a major clinical problem. Owing to the dynamic nature of the epigenome, the identification and targeting of potential epigenetic modifiers may be helpful to curb radio-resistance. This requires a detailed exploration of the epigenetic chan...

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Detalles Bibliográficos
Autores principales: Sharda, Asmita, Rashid, Mudasir, Shah, Sanket Girish, Sharma, Ajit Kumar, Singh, Saurav Raj, Gera, Poonam, Chilkapati, Murali Krishna, Gupta, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942324/
https://www.ncbi.nlm.nih.gov/pubmed/31900196
http://dx.doi.org/10.1186/s13148-019-0800-4

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