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Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3β signalling pathway in renal cell carcinoma

BACKGROUND: Clinically, the median survival in patients with metastatic renal cell carcinoma (RCC) was only 6–12 months and a 5-year survival rate of less than 20%. Therefore, an in-depth study of the molecular mechanisms involved in RCC is of great significance for improving the survival of patient...

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Detalles Bibliográficos
Autores principales: Zhu, Qian, Zhong, Ai-Lin, Hu, Hao, Zhao, Jing-Jing, Weng, De-Sheng, Tang, Yan, Pan, Qiu-Zhong, Zhou, Zi-Qi, Song, Meng-Jia, Yang, Jie-Ying, He, Jun-Yi, Liu, Yuan, Li, Min, Hu, Wan-Ming, Yang, Chao-Pin, Xiang, Tong, Chen, Ming-Yuan, Ma, Gang, Guo, Ling, Xia, Jian-Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942383/
https://www.ncbi.nlm.nih.gov/pubmed/31900208
http://dx.doi.org/10.1186/s13045-019-0840-4