The emerging role of SPOP protein in tumorigenesis and cancer therapy

The nuclear speckle-type pox virus and zinc finger (POZ) protein (SPOP), a representative substrate-recognition subunit of the cullin-RING E3 ligase, has been characterized to play a dual role in tumorigenesis and cancer progression. Numerous studies have determined that SPOP suppresses tumorigenesi...

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Detalles Bibliográficos
Autores principales: Song, Yizuo, Xu, Yichi, Pan, Chunyu, Yan, Linzhi, Wang, Zhi-wei, Zhu, Xueqiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942384/
https://www.ncbi.nlm.nih.gov/pubmed/31901237
http://dx.doi.org/10.1186/s12943-019-1124-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942384/
https://www.ncbi.nlm.nih.gov/pubmed/31901237
http://dx.doi.org/10.1186/s12943-019-1124-x

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