Lactate‐fueled oxidative metabolism drives DNA methyltransferase 1‐mediated transcriptional co‐activator with PDZ binding domain protein activation

Activity of transcriptional co‐activator with PDZ binding domain (TAZ) protein is strongly implicated in the pathogenesis of human cancer and is influenced by tumor metabolism. High levels of lactate concentration in the tumor microenvironment as a result of metabolic reprogramming are inversely cor...

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Detalles Bibliográficos
Autores principales: Huang, Tao, Zhou, Xinglu, Mao, Xike, Yu, Chenxi, Zhang, Zhijian, Yang, Jianke, Zhang, Yao, Su, Tianyu, Chen, Chenchen, Cao, Yuxiang, Wei, Huijun, Wu, Zhihao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942427/
https://www.ncbi.nlm.nih.gov/pubmed/31746077
http://dx.doi.org/10.1111/cas.14246

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