Quantitative monitoring of circulating tumor DNA in patients with advanced pancreatic cancer undergoing chemotherapy

According to cancer genome sequences, more than 90% of cases of pancreatic ductal adenocarcinoma (PDAC) harbor active KRAS mutations. Digital PCR (dPCR) enables accurate detection and quantification of rare mutations. We assessed the dynamics of circulating tumor DNA (ct‐DNA) in patients with advanc...

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Detalles Bibliográficos
Autores principales: Sugimori, Makoto, Sugimori, Kazuya, Tsuchiya, Hiromi, Suzuki, Yoshimasa, Tsuyuki, Sho, Kaneta, Yoshihiro, Hirotani, Akane, Sanga, Katsuyuki, Tozuka, Yuichiro, Komiyama, Satoshi, Sato, Takeshi, Tezuka, Shun, Goda, Yoshihiro, Irie, Kuniyasu, Miwa, Haruo, Miura, Yuuki, Ishii, Tomohiro, Kaneko, Takashi, Nagahama, Masatsugu, Shibata, Wataru, Nozaki, Akito, Maeda, Shin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6942439/
https://www.ncbi.nlm.nih.gov/pubmed/31746520
http://dx.doi.org/10.1111/cas.14245

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